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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA3
All Species:
51.21
Human Site:
Y467
Identified Species:
70.42
UniProt:
P30101
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30101
NP_005304.3
505
56782
Y467
K
K
L
N
P
K
K
Y
E
G
G
R
E
L
S
Chimpanzee
Pan troglodytes
XP_001159528
485
54945
Y447
K
K
L
N
P
K
K
Y
E
G
G
R
E
L
S
Rhesus Macaque
Macaca mulatta
XP_001108948
480
54081
Y442
K
K
L
N
P
K
K
Y
E
G
G
R
E
L
S
Dog
Lupus familis
XP_535453
687
75990
Y649
K
K
L
N
P
K
K
Y
E
G
G
R
E
L
S
Cat
Felis silvestris
Mouse
Mus musculus
P27773
505
56660
Y467
K
K
L
T
P
K
K
Y
E
G
G
R
E
L
N
Rat
Rattus norvegicus
P11598
505
56605
Y467
K
K
L
T
P
K
K
Y
E
G
G
R
E
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517928
483
54617
Y444
K
K
Q
S
P
K
K
Y
E
G
G
R
E
V
S
Chicken
Gallus gallus
Q8JG64
505
56163
Y465
K
K
Q
S
P
K
K
Y
E
G
G
R
E
V
S
Frog
Xenopus laevis
NP_001080051
502
56103
Y464
N
K
Q
N
P
K
R
Y
E
G
G
R
E
V
S
Zebra Danio
Brachydanio rerio
NP_998070
488
54656
Y458
Q
K
D
Q
P
R
R
Y
E
G
G
R
E
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
L458
N
K
V
I
D
F
N
L
D
R
T
L
D
D
F
Honey Bee
Apis mellifera
XP_623282
490
55838
Y452
S
K
N
N
P
V
K
Y
E
G
G
R
E
L
D
Nematode Worm
Caenorhab. elegans
P34329
618
69779
Y591
K
K
S
E
P
I
K
Y
S
G
N
R
D
L
E
Sea Urchin
Strong. purpuratus
XP_782981
472
51996
Y442
N
K
S
S
P
K
K
Y
E
G
G
R
E
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
S469
G
K
V
T
S
Y
D
S
G
R
T
A
D
D
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
E463
S
G
N
V
V
V
Y
E
G
D
R
T
K
E
D
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
Y467
K
K
S
E
S
V
V
Y
Q
G
S
R
S
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
94.4
70.8
N.A.
93
92.2
N.A.
84.7
80.9
74.6
60
N.A.
32.6
49.5
36.7
50.5
Protein Similarity:
100
92.6
94.8
72.1
N.A.
97
96.2
N.A.
90.3
90.8
88.3
77.2
N.A.
53.4
63.7
50.4
65.9
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
80
80
73.3
53.3
N.A.
6.6
73.3
53.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
86.6
86.6
N.A.
26.6
73.3
60
80
Percent
Protein Identity:
N.A.
34.3
N.A.
35.6
26.8
N.A.
Protein Similarity:
N.A.
51
N.A.
54.9
48.4
N.A.
P-Site Identity:
N.A.
6.6
N.A.
0
40
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
6
0
6
0
6
0
6
6
0
0
18
12
18
% D
% Glu:
0
0
0
12
0
0
0
6
71
0
0
0
71
6
6
% E
% Phe:
0
0
0
0
0
6
0
0
0
0
0
0
0
0
6
% F
% Gly:
6
6
0
0
0
0
0
0
12
83
71
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
6
0
6
0
0
0
0
0
0
0
0
6
% I
% Lys:
59
95
0
0
0
59
65
0
0
0
0
0
6
0
0
% K
% Leu:
0
0
36
0
0
0
0
6
0
0
0
6
0
53
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
18
0
12
36
0
0
6
0
0
0
6
0
0
0
18
% N
% Pro:
0
0
0
0
77
0
0
0
0
0
0
0
0
0
6
% P
% Gln:
6
0
18
6
0
0
0
0
6
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
6
12
0
0
12
6
83
0
0
0
% R
% Ser:
12
0
18
18
12
0
0
6
6
0
6
0
6
0
42
% S
% Thr:
0
0
0
18
0
0
0
0
0
0
12
6
0
0
0
% T
% Val:
0
0
12
6
6
18
6
0
0
0
0
0
0
30
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
6
6
83
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _